In this post, let’s have a look at the error message “5.7.750 – Service unavailable. Client blocked from sending from unregistered domains” that you get when working with Microsoft 365 Exchange Online.
These are the errors that you usually receive when there is a problem in delivering the email message that was sent by you. These errors are generated and sent by Office 365. This is usually alled as DSN which stands for delivery status notification or in simple words bounce messages.
NDR or Non-delivery report is one of the common type of message that you receive which indicates to the user that the email was not delivered.
5.7.750 – Service unavailable. Client blocked from sending from unregistered domains
A suspicious number of messages from unprovisioned domains is coming from this tenant.
Add and validate any and all domains that you use to send email from Microsoft 365 or Office 365.
For more information, see Fix email delivery issues for error codes 5.7.700 through 5.7.750 in Exchange Online.