In this blog post, you’ll learn more about the Sybase Error Cannot change the setting of the SingleCLRInstanceVersion server option after the CLR external environment has already been started and the reason for receiving this error
Sybase SQL Error Message
Cannot change the setting of the SingleCLRInstanceVersion server option after the CLR external environment has already been started
Reason for this Error
You attempted to change the setting of the SingleCLRInstanceVersion server option after starting a CLR external environment. Restart the database server to change this server option.